乳业科学与技术 ›› 2025, Vol. 48 ›› Issue (1): 24-29.DOI: 10.7506/rykxyjs1671-5187-20240724-064

• 专题论述 • 上一篇    下一篇

乳脂肪球膜蛋白组成、理化性质及生物活性研究进展

梁佳迎,张海迁,纪友薇,江婷,张涛,潘道东,吴振   

  1. (宁波大学食品科学与工程学院,浙江 宁波 315000)
  • 出版日期:2025-01-01 发布日期:2025-02-28
  • 基金资助:
    国家自然科学基金面上项目(32072192;32402125);浙江省杰出青年科学基金项目(LR22C200001); 浙江省教育厅一般项目(Y202352124); 省部共建农产品质量安全危害因子与风险防控国家重点实验室开放基金项目(2021DG700024-KF202423)

Advances in Composition, Physicochemical Properties and Bioactivity of Milk Fat Globule Membrane Proteins

LIANG Jiaying, ZHANG Haiqian, JI Youwei, JIANG Ting, ZHANG Tao, PAN Daodong, WU Zhen   

  1. (College of Food Science and Engineering, Ningbo University, Ningbo 315000, China)
  • Published:2025-01-01 Online:2025-02-28

摘要: 乳脂肪球膜(milk fat globule membrane,MFGM)是乳中包裹乳脂肪球的3 层生物膜,主要成分包括蛋白质、糖类和主要来源于乳腺细胞膜的脂质。MFGM蛋白组成因乳源不同而存在差异,MFGM蛋白不仅具有良好的乳化性能、胃肠消化稳定性及安全性等,其特定蛋白组分还具备抗炎、抗病毒、调节肠道功能、优化运动肌肉表现等多种生物活性。本文综述MFGM蛋白组成及其理化性质和生物活性,为MFGM蛋白在乳品行业及相关食品添加中的研究和应用提供一定的参考。

关键词: 乳脂肪球;脂肪球膜蛋白;结构;生物活性

Abstract: The milk fat globule membrane (MFGM) is a three-layered membrane that surrounds milk fat globules. Its main components include proteins, carbohydrates, and lipids, which are mainly derived from the mammary gland cell membrane. Different milk sources vary in the composition of MFGM proteins, which have good emulsifying properties, gastrointestinal stability and safety. Some MFGM proteins have diverse bioactivities including anti-inflammatory, antiviral and intestine regulatory effects and enhancing the exercise performance of muscles. This paper reviews the composition, physicochemical properties and bioactivities of MFGM proteins, which will provide a reference for the research and application of MFGM proteins in the dairy industry and related food additives.

Key words: milk fat globules; fat globule membrane proteins; structure; bioactivities

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