乳业科学与技术 ›› 2025, Vol. 48 ›› Issue (1): 60-68.DOI: 10.7506/rykxyjs1671-5187-20241008-091

• 专题论述 • 上一篇    

蛋白质组学技术在解析牛乳清蛋白代谢途径和生物功能中的应用研究进展

傅汐,陈金叶,顾颖,赵琼   

  1. (1.昆明理工大学食品科学与工程学院,云南 昆明 650500;2.云南乍甸乳业有限责任公司,云南 红河 675999)
  • 出版日期:2025-01-01 发布日期:2025-02-28
  • 基金资助:
    云南省重大科技专项(202402AE090040)

Advances in the Application of Proteomics in Analyzing Metabolic Pathways and Biological Functions of Bovine Whey Proteins

FU Xi, CHEN Jinye, GU Ying, ZHAO Qiong   

  1. (1. Faculty of Food Science and Engineering, Kunming University of Science and Technology, Kunming 650500, China; 2. Yunnan Zhadian Dairy Co. Ltd., Honghe 675999, China)
  • Published:2025-01-01 Online:2025-02-28

摘要: 乳清蛋白作为乳中的优质蛋白,具有丰富的营养价值和功能特性。乳清蛋白会因不同环境下物种的遗传变异和蛋白翻译后修饰导致表达量和结构的差异,使得其种类繁多而又复杂,给深入了解乳清蛋白增加了难度。随着组学技术的不断发展,人们对乳清蛋白的组成和功能活性有了更深入的了解。本文综述蛋白质组学技术在牛乳清蛋白研究中的应用,解析不同牛种、泌乳期、饲养条件和处理方式下乳清蛋白的种类、分子结构、代谢途径及生物功能之间的异同,以期为牛乳清蛋白的深入研究及个性化乳制品的研制提供科学的理论依据。

关键词: 蛋白质组学;牛乳清蛋白;分子结构;代谢途径;生物功能

Abstract: Whey proteins, as high-quality proteins in milk, have high nutritional value and diverse functional properties. Genetic variations under different environments and post-translational modifications cause differences in the expression and structure of whey proteins, resulting in an increased diversity and complexity, which makes it more difficult to gain insights into whey proteins. With the continuous development of omics techniques, people have gained a deeper understanding of the composition and functional activities of whey proteins. With a view to providing a scientific theoretical basis for in-depth studies of bovine whey proteins and the development of personalized dairy products, this paper reviews the application of proteomics in the study of bovine whey proteins, and analyzes the similarities and differences in the types, molecular structures, metabolic pathways, and biological functions of whey proteins from different breeds of cow, lactation periods, feeding conditions, and processing methods.

Key words: proteomics; bovine whey proteins; molecular structure; metabolic pathways; biological functions

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