关键词: 母乳低聚糖, 唾液酸乳糖, 双歧杆菌, 肠道菌群, 摄取与代谢

Abstract: Human Milk Oligosaccharides (HMOs) are important nutritional components in milk, and sialyllactose(SL) is one of the core members of HMOs. HMOs play an important role in regulating the gut microbiota of infants, especially in the reproduction and metabolic regulation of the dominant gut microbiota in early life - Bifidobacterium. SL has diverse sources and preparation methods, providing multiple alternative pathways for industrial applications. However, the interaction mechanism between SL and Bifidobacterium is complex, and there are still many difficulties that need to be overcome, which affects the combined application of SL and Bifidobacterium in food and other industrial development. Therefore, this review provides three aspects: the source pathway of SL, the carbohydrate uptake behavior and HMOs metabolism of Bifidobacterium, and the mechanism of SL on Bifidobacterium. The aim is to provide scientific reference for further promoting the development of SL in the field of breast milk substitutes and functional foods.

Key words: Human milk oligosaccharides, Sialyllactose, Bifidobacterium, Gut microbiota, Intake and metabolism