Abstract: As the most common type of anemia, iron-deficiency anemia has attracted more and more attention. With the change of nutrition and health needs and the enhancement of safety awareness, there has been increasing interest in the research and development of oral iron supplements with good iron supplementation effect, easy absorption, small side effects and high safety. This paper reviews recent progress in the development and research of iron supplements. In this paper, the raw material source, structure, action mechanism, preparation, application, and digestion and absorption mechanism of iron protein succinate are reviewed, and future prospects of polypeptide-iron complexes and iron protein succinate are discussed. We anticipate that this review will provide a theoretical basis for the research and development of iron supplements.

Key words: iron supplements; polypeptide-iron complexes; iron protein succinate; yak milk casein

摘要： 缺铁性贫血作为贫血中最常见的一种，越来越受到人们的关注。随着营养与健康需求的变化和安全意识的 增强，人们致力于补铁效果好、吸收好、副作用小、安全性更高的口服补铁剂的研发。本文对补铁剂的发展和相关 研究进行综述，概述新型补铁剂的研究进展，全面阐述多肽铁复合物蛋白琥珀酸铁的原料来源、结构、机理、制 备、应用、消化吸收机制，对多肽铁复合物和蛋白琥珀酸铁的发展前景进行展望，以期对补铁剂的研究与发展提供 理论依据。

关键词: 补铁剂；多肽铁复合物；蛋白琥珀酸铁；牦牛乳酪蛋白