Abstract: Breast milk is the most ideal natural food for infants and the gold standard for the development of infant formula (IF). Accurately simulating the nutritional components of breast milk is an important means to improve IF. In order to better simulate breast milk lipids, a new generation of IF was developed based on the reported breast milk data, and then the total fatty acids and sn-2 fatty acids in breast milk and the new generation of IF were comparatively analyzed. The results showed that the new generation of IF and human milk were highly similar in total fatty acids and sn-2 fatty acids (the similarity coefficients were > 85% and > 70%, respectively). In conclusion, the new generation of IF can accurately simulate the total fatty acids and sn-2 fatty acids in human milk.

Key words: breast milk; fatty acids; infant formula; similarity evaluation; sn-2 fatty acids

摘要： 母乳是婴儿最理想的天然食品，也是婴幼儿配方乳粉（infant formula，IF）开发的金标准。精准模拟母乳的营养组分，是实现IF产品提升的一种重要手段。为更好模拟母乳脂质，依据已报道的母乳数据开发了新一代IF，然后对比分析母乳和新一代IF中总脂肪酸和sn-2脂肪酸与母乳的相似性。结果表明：新一代IF和母乳在总脂肪酸和sn-2脂肪酸组成上具有高度相似性（相似性系数分别为＞85%和＞70%），表明新一代IF实现了对母乳总脂肪酸和sn-2脂肪酸的高度模拟。

关键词: 母乳；脂肪酸；婴幼儿配方乳粉；相似性评价；sn-2脂肪酸