Abstract: Milk occupies an important position in the human diet structure, while some studies indicated residues of various veterinary drugs in commercial milk. Meanwhile, detection of veterinary drug residues is difficult due to the complexity of milk matrix. As development of separation techniques based on magnetic materials has become a hot topic for international researchers, magnetic solid-phase extraction (MSPE) as a new mode of solid-phase extraction (SPE) has powerful advantages in the field of separation science due to its superparamagnetic character and adsorption selectivity. This paper describes the new SPE technique and reviews its current applications in the detection of veterinary drug residues in milk.

Key words: milk；veterinary drug residues；current applications

摘要： 由于牛奶基质的复杂性,为牛奶中兽药残留检测造成了诸多困难.基于磁性材料的分离技术是近年来国内外研究的一个热点,磁性固相萃取技术(MSPE)作为固相萃取(SPE)的一种新型模式,以其超顺磁性和选择吸附性,在分离科学领域展现出了强大的优势.本文对MSPE技术进行了简介,并对其在牛奶兽药残留检测分析中的应用进展进行综述.

关键词: 磁性固相萃取技术；牛奶；兽药残留；应用进展