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乳业科学与技术 ›› 2021, Vol. 44 ›› Issue (1): 13-17.DOI: 10.15922/j.cnki.jdst.2021.01.003

• 基础研究 • 上一篇    下一篇

母乳低聚糖组成及其对益生菌的增殖作用

揭良, 苏米亚, 贾宏信, 陈文亮, 齐晓彦   

  1. （乳业生物技术国家重点实验室，上海乳业生物工程技术研究中心，光明乳业股份有限公司乳业研究院，上海 200436）
  • 出版日期:2021-01-01 发布日期:2021-11-01
  • 基金资助:
    “十三五”国家重点研发计划重点专项（2018YFC1604205）； 上海市科学技术委员会科研计划项目（17391901100）；上海乳业生物工程技术研究中心项目（19DZ2281400）

Oligosaccharide Composition of Human Breast Milk and Its Effect on Promoting the Proliferation of Probiotics

JIE Liang, SU Miya, JIA Hongxin, CHEN Wenliang, QI Xiaoyan   

  1. (Shanghai Engineering Research Center of Dairy Biotechnology, State Key Laboratory of Dairy Biotechnology, Dairy Research Institute, Bright Dairy and Food Co. Ltd., Shanghai 200436, China)
  • Online:2021-01-01 Published:2021-11-01

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摘要： 研究混合母乳中复杂的母乳低聚糖（human milk oligosaccharides，HMOs）组成及含量，选择双歧杆菌Bb-12、发酵乳杆菌CECT5716 2 种益生菌，研究HMOs 2’-岩藻糖（2’-fucosyllactose，2’-FL）对2 种益生菌的增殖作用。结果表明：2 个混合样本的HMOs含量分别为10.613、5.093 g/L，差异很大，说明不同母乳来源的HMOs受诸多因素影响，但含量范围一般为5～15 g/L；2’-FL对发酵乳杆菌CECT5716和双歧杆菌Bb-12均有

关键词: 母乳, 母乳低聚糖, 益生菌增殖, 双歧杆菌, 发酵乳杆菌

Abstract: The composition and contents of oligosaccharides in two mixed samples of human breast milk were determined and the effect of the human milk oligosaccharides (HMOs) 2’-fucosyllactose (2’-FL) on the proliferation of two probiotic strains, Bifidobacterium Bb-12 and Lactobacillus fermentum CECT5716 was evaluated in this study. The results showed that the HMOs contents of the two mixed samples were 10.613 and 5.093 g/L respectively. This significant difference indicated that HMOs contents in breast milk from different mothers are affected by many factors, generally ranging between 5 and 15 g/L. 2’-FL promoted the growth of both priobiotics, indicating that the probiotics could utilize HMOs for growth and proliferation.

Key words: human milk, human milk oligosaccharides, proliferation of probiotics, Bifidobacterium, Lactobacillus fermentum

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