Abstract: Functional constipation is a clinically common digestive system syndrome, which can cause a series of diseases. Therefore the prevention and treatment of this disease is of great significance. Bifidobacterium is one of the inherent flora in the human intestinal tract, which has been proved to have a significant alleviating effect on functional constipation. This review discussed the recent progress in understanding the alleviating effect of Bifidobacterium on functional constipation with respect to the relationship between the intestinal microbiota and functional constipation, the mechanism of Bifidobacterium in alleviating constipation and the efficacy of various Bifidobacterium strains, in order to provide research ideas for the in-depth development of functional Bifidobacteria strains and for understanding their mechanism in alleviating constipation.

Key words: Bifidobacterium, functional constipation, digestive system syndrome, intestinal microbiota

摘要： 功能性便秘是一种临床上比较常见的消化系统疾病，可引发一系列疾病，因此对该疾病的预防和治疗具有重要意义。双歧杆菌是肠道固有菌群之一，其对缓解功能性便秘有明显效果。本文从肠道菌群与功能性便秘的关系、双歧杆菌缓解便秘的机制以及双歧杆菌不同菌株缓解功能性便秘的效果等方面对双歧杆菌缓解功能性便秘的国内外研究进展进行综述，以期为双歧杆菌功能性菌株的深度开发及其用于缓解便秘机制的深入研究提供思路。

关键词: 双歧杆菌, 功能性便秘, 消化系统疾病, 肠道微生态