关键词: 动物细胞核; 功能蛋白质组学

Abstract: The nucleus is the control center for the cell genetics and metabolism.Functional proteomics of the nucleus has become a hot topic in proteomic research.The nucleus contains many functional proteins,some of which are involved in transcriptional regulation while others are involved in nuclear-cytoplasmic transport.Proteomic detection of the state-specific activity of functional proteins is of great significance to insightful understanding of the molecular mechanisms underlying gene expression and regulation.This paper provides a review of the current research situation of functional proteomics of the cell nucleus.

Key words: nucleus;functional proteomics;